Tuesday, March 24, 2009

Raloxifene



raloxifene
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  Raloxifene is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women. It was announced on April 17, 2006, that raloxifene is as effective as tamoxifen in reducing the incidence of breast cancer in certain high risk groups of females, though with a reduced risk of thromboembolic events and cataracts in patients taking raloxifene versus Osteoporosis is a disease wherein bones become fragile or porous and thus brittle, leading to easy fractures. A bone mineral density test (BMD) is the only way one can diagnose osteoporosis and thus determine any risks for future fracture. The main reason BMD has to be done is because osteoporosis can go undetected for decades [...]

Author: rayburnlurzfiryp
Keywords: health
Added: September 30, 2008

Eli Lilly announced that new data from a late-stage trial showed that its investigational drug arzoxifene was superior to Evista (raloxifene) at increasing bone mineral density (BMD) in the lumbar spine. The findings were presented at the annual meeting of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ECCEO). The NEXT study involved 320 post-menopausal women with osteoporosis who were randomised to receive daily doses of either arzoxifene or Evist

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